Title
The Genome Of The Sea Urchin Strongylocentrotus Purpuratus
Abstract
We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.
Publication Date
11-10-2006
Publication Title
Science
Volume
314
Issue
5801
Number of Pages
941-952
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1126/science.1133609
Copyright Status
Unknown
Socpus ID
33750995860 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/33750995860
STARS Citation
Sodergren, Erica; Weinstock, George M.; Davidson, Eric H.; Cameron, R. Andrew; and Gibbs, Richard A., "The Genome Of The Sea Urchin Strongylocentrotus Purpuratus" (2006). Scopus Export 2000s. 7853.
https://stars.library.ucf.edu/scopus2000/7853