Title

A Water-Soluble Diaminostilbene Derivative As A Two-Photon Fluorescent Probe

Keywords

Fluorescent probe; PAMAM: hydrophilic; Two-photon; Two-photon microscopy; Z-scan

Abstract

A hydrophilic trans-4,4′-diaminostilbene derivative was prepared by the introduction of amideamino peripheral substituents. Very high aqueous solubility was achieved (>15 mM), making it possible as a fluorescent probe for biological imaging. The relatively straightforward synthetic methodology has great potential to transform even large hydrophobic two-photon absorbing chromophores into hydrophilic derivatives. The fluorescence quantum yield of 0.27 for the diaminostilbene in water is sufficiently high for use as a fluorescent probe. In addition, two-photon fluorescence images of NT2 cells stained by this probe were also obtained. © Georg Thieme Verlag Stuttgart.

Publication Date

8-1-2006

Publication Title

Synlett

Issue

12

Number of Pages

1863-1866

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1055/s-2006-948165

Socpus ID

33747066727 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/33747066727

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