Title

Schizophrenia And Red Light: Fmri Evidence For A Novel Biobehavioral Marker

Keywords

Biobehavioral marker; Endophenotype; First-degree relatives; Functional magnetic resonance imaging; Magnocellular visual pathway; Red light

Abstract

Previous research has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual pathway. An earlier psychophysical study found that a subset of nonpsychotic relatives of persons with schizophrenia showed the opposite effect when compared to healthy adults (Bedwell et al., 2003), suggesting a novel biobehavioral marker for the disorder. The present study attempted to replicate and explore the mechanism for this effect using fMRI. Results provide physiological evidence that the M pathway response to red light is in the opposite direction than expected in a subset of nonpsychotic relatives of persons with schizophrenia. Copyright © 2006 Informa Healthcare.

Publication Date

8-1-2006

Publication Title

International Journal of Neuroscience

Volume

116

Issue

8

Number of Pages

881-894

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1080/00207450500516529

Socpus ID

33746599911 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/33746599911

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