Title

Three-Photon Absorption Measurements In Hematoporphyrin Ix: "Ground-Breaking Opportunities In Deep Photodynamic Therapy"

Abstract

In this Letter, we report the three-photon absorption of hematoporphyrin IX (HpD-IX) in DMSO solution pumping at 1200 nm with a 25 ps pulse laser-OPG system. The obtained three-photon absorption cross-section in HpD-IX, σ3′=1.2×10-78cm6s2ph-2, is considerably high. Because HpD-IX is one of the main constituent of Photofrin® II, the only approved photodynamic therapy drug by the Food and Drug Association, this result is expected to have an impact in deep bioimaging and photodynamic therapy using currently available photosensitisers. © 2005 Elsevier B.V. All rights reserved.

Publication Date

2-15-2006

Publication Title

Chemical Physics Letters

Volume

419

Issue

1-3

Number of Pages

33-36

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.cplett.2005.11.051

Socpus ID

31544458147 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/31544458147

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