Title

Synthesis And Characterization Of New Fluorene-Based Singlet Oxygen Sensitizers

Keywords

Photodynamic therapy; Photosensitizer; Singlet oxygen; Two-photon absorption

Abstract

The synthesis, photophysical characterization, and determination of singlet oxygen quantum yields (Φ Δ) for a class of fluorene derivatives with potential application in two-photon photodynamic therapy (PDT) is reported. It has been demonstrated that these compounds possess the ability to generate singlet oxygen ( 1O 2) upon excitation. A photochemical method, using 1,3-diphenylisobenzofuran (DPBF) as 1O 2 chemical quencher, was employed to determine the singlet oxygen quantum yields (Φ Δ) of the fluorene-based photosensitizers in ethanol. Φ Δ values ranged from 0.35 to 0.75. These derivatives may have potential application as two-photon photosensitizers when pumped via two-photon excitation in the near-IR spectral region. © 2006 Springer Science+Business Media, Inc.

Publication Date

1-1-2006

Publication Title

Journal of Fluorescence

Volume

16

Issue

1

Number of Pages

105-110

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/s10895-005-0008-1

Socpus ID

33645667859 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/33645667859

This document is currently not available here.

Share

COinS