Title

Nucleic Acid Detection Using Mnazymes

Abstract

Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reported on the design of multi-component deoxyribozyme (MNAzyme) sensors based on 10-23 and 8-17 DNA enzymes. The sensors can detect down to 5 pM of a specific nucleic acid. The versatility of MNAzyme platform allows the design of catalytic cascades for signal amplification. This work is a step forward to PCR-free molecular diagnostics. © 2010 Elsevier Ltd. All rights reserved.

Publication Date

2-26-2010

Publication Title

Chemistry and Biology

Volume

17

Issue

2

Number of Pages

104-106

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.chembiol.2010.02.003

Socpus ID

77049121311 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/77049121311

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