Title

Osteogenesis Imperfecta In The Archeological Record: An Example From The Dakhleh Oasis, Egypt

Keywords

Dakhleh Oasis; Differential diagnosis; Egypt; Fetal skeletal remains; Osteogenesis imperfecta; Paleopathology

Abstract

The present study evaluates a fetal skeleton (B532) from the Romano-Byzantine period Kellis 2 cemetery (circa A.D. 50-A.D. 450), in the Dakhleh Oasis, Egypt. This skeleton displays abnormal skeletal characteristics consisting of severe bowing of the long bones. Differential diagnoses using macroscopic and radiographic analyses indicate that this individual's pathological condition was caused by osteogenesis imperfecta (IO), possibly Type IIB/III, or Type IV OI, corroborating with characteristics reported in the clinical literature. Due to the severe bowing of the long bones, traditional aging methods could not be used for this individual. Baysian estimates of age indicate this individual was a fetus of approximately 38 weeks gestation. Although this condition has been diagnosed previously in the archeological literature, this burial represents the youngest aged example of osteogenesis imperfecta reported to date. © 2012 Elsevier Inc..

Publication Date

12-1-2011

Publication Title

International Journal of Paleopathology

Volume

1

Issue

3-4

Number of Pages

188-199

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.ijpp.2012.02.001

Socpus ID

84859438100 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84859438100

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