Title
Pegylated Inorganic Nanoparticles
Keywords
metal oxides; nanoparticles; nanotherapeutics; PEGylation; surface modification
Abstract
Application of inorganic nanoparticles in diagnosis and therapy has become a critical component in the targeted treatment of diseases. The surface modification of inorganic oxides is important for providing diversity in size, shape, solubility, long-term stability, and attachment of selective functional groups. This Minireview describes the role of polyethylene glycol (PEG) in the surface modification of oxides and focuses on their biomedical applications. Such a PEGylation of surfaces provides "stealth" characteristics to nanomaterials otherwise identified as foreign materials by human body. The role of PEG as structure-directing agent in synthesis of oxides is also presented. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication Date
2-25-2011
Publication Title
Angewandte Chemie - International Edition
Volume
50
Issue
9
Number of Pages
1980-1994
Document Type
Review
Personal Identifier
scopus
DOI Link
https://doi.org/10.1002/anie.201002969
Copyright Status
Unknown
Socpus ID
79951861958 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/79951861958
STARS Citation
Karakoti, Ajay S.; Das, Soumen; Thevuthasan, Suntharampillai; and Seal, Sudipta, "Pegylated Inorganic Nanoparticles" (2011). Scopus Export 2010-2014. 3327.
https://stars.library.ucf.edu/scopus2010/3327