Title

Current Status Of Salvage Robot-Assisted Laparoscopic Prostatectomy For Radiorecurrent Prostate Cancer

Keywords

Brachytherapy; Endourology; Prostate cancer; Radiation failure; Radiation therapy; Radiorecurrent prostate cancer; Recurrence; Salvage robot-assisted laparoscopic prostatectomy; sRALP; Surgery

Abstract

Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low-dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40-60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryo-therapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30-40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomot-ic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP. © Springer Science+Business Media, LLC 2012.

Publication Date

6-1-2012

Publication Title

Current Urology Reports

Volume

13

Issue

3

Number of Pages

195-201

Document Type

Review

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/s11934-012-0245-1

Socpus ID

84864831641 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84864831641

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