Title

Computational Fluid Dynamics Modeling Of Airflow Inside Lungs Using Heterogenous Anisotropic Lung Tissue Elastic Properties

Keywords

Fluid flow analysis; Lung modeling; Organ dynamics

Abstract

The aim of this paper is to model the airflow inside lungs during breathing and its fluid-structure interaction with the lung tissues and the lung tumor using subject-specific elastic properties. The fluid-structure interaction technique simultaneously simulates flow within the airway and anisotropic deformation of the lung lobes. The three-dimensional (3D) lung geometry is reconstructed from the end-expiration 3D CT scan datasets of humans with lung cancer. The lung is modeled as a poro-elastic medium with anisotropic elastic property (non-linear Young's modulus) obtained from inverse lung elastography of 4D CT scans for the same patients. The predicted results include the 3D anisotropic lung deformation along with the airflow pattern inside the lungs. The effect is also presented of anisotropic elasticity on both the spatio-temporal volumetric lung displacement and the regional lung hysteresis. © 2012 The authors and IOS Press. All rights reserved.

Publication Date

1-1-2012

Publication Title

Studies in Health Technology and Informatics

Volume

173

Number of Pages

205-211

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

DOI Link

https://doi.org/10.3233/978-1-61499-022-2-205

Socpus ID

84860634662 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84860634662

This document is currently not available here.

Share

COinS