Title

Measuring Anisotropic Cell Motility On Curved Substrates

Keywords

Cell motility; Difference imaging; Mechanical stimuli; Motility assay

Abstract

Schwann cell motility was observed on laminin-coated quartz cylinders with different curvatures over an 18 hour period. A new analysis based on difference images helped to determine the minimal radius of curvature, 46 μm, which restricted motility along the cylinder axis. The migration speed, measured by calculating differences between successive images in the time series, ranged between 0.3 to 0.8 μm per minute and is similar to previously reported rates for Schwann cells. Difference images provide a rapid and simple method for the analysis of cell motility on large populations of cells. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Publication Date

5-1-2013

Publication Title

Journal of Biophotonics

Volume

6

Issue

5

Number of Pages

387-392

Document Type

Letter

Personal Identifier

scopus

DOI Link

https://doi.org/10.1002/jbio.201200089

Socpus ID

84877150066 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84877150066

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