Title

Detection Of Snp-Containing Human Dna Sequences Using A Split Sensor With A Universal Molecular Beacon Reporter

Keywords

DNA junctions; Forensic SNPs; Genotyping; High specificity; Molecular beacon probe

Abstract

Hybridization-based techniques have been extensively employed for the analysis of specific DNA/RNA sequences. Herein, we describe highly specific inexpensive smart hybridization-based sensor that takes advantage of a universal molecular beacon probe as a fluorescent reporter. The sensor has a straightforward design, and demonstrates improved selectivity and specificity of nucleic acid recognition. It is cost-efficient since it utilizes the same molecular beacon probe for the analysis of many nucleic acid sequences. © 2013 Springer Science+Business Media, New York.

Publication Date

1-1-2013

Publication Title

Methods in Molecular Biology

Volume

1039

Number of Pages

69-80

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/978-1-62703-535-4_5

Socpus ID

84934444501 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84934444501

This document is currently not available here.

Share

COinS