Title

Breast-Feeding After Transplantation

Keywords

breast milk; breast-feeding; immunosuppression; lactation; transplant

Abstract

Transplantation affords recipients the potential for a full life and, for some, parenthood. Female transplant recipients must continue to take immunosuppression during pregnancy and breast-feeding. This article reviews case and series reports regarding breast-feeding in those taking transplant medications. Avoidance of breast-feeding has been the customary advice because of the potential adverse effects of immunosuppressive exposure on the infant. Subsequent studies have demonstrated that not all medication exposure translates to risk for the infant, that the exposure in utero is greater than via breast milk and that no lingering effects due to breast-feeding have been found to date in infants who were breast-fed while their mothers were taking prednisone, azathioprine, cyclosporine, and/or tacrolimus. Thus, except for those medications where clinical information is inadequate (mycophenolic acid products, sirolimus, everolimus, and belatacept), the recommendation for transplant recipients regarding breast-feeding has evolved into one that is cautiously optimistic.

Publication Date

11-1-2014

Publication Title

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volume

28

Issue

8

Number of Pages

1163-1173

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.bpobgyn.2014.09.001

Socpus ID

84927136051 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84927136051

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