Title
Mechanisms For Control Of Biological Electron Transfer Reactions
Keywords
Amicyanin; Coupled electron transfer; Electronic coupling; Gated electron transfer; Hole hopping; MauG; Quinoprotein; Reorganization energy
Abstract
Electron transfer (ET) through and between proteins is a fundamental biological process. The rates and mechanisms of these ET reactions are controlled by the proteins in which the redox centers that donate and accept electrons reside. The protein influences the magnitudes of the ET parameters, the electronic coupling and reorganization energy that are associated with the ET reaction. The protein can regulate the rates of the ET reaction by requiring reaction steps to optimize the system for ET, leading to kinetic mechanisms of gated or coupled ET. Amino acid residues in the segment of the protein through which long range ET occurs can also modulate the ET rate by serving as staging points for hopping mechanisms of ET. Specific examples are presented to illustrate these mechanisms by which proteins control rates of ET reactions.
Publication Date
1-1-2014
Publication Title
Bioorganic Chemistry
Volume
57
Number of Pages
213-221
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1016/j.bioorg.2014.06.006
Copyright Status
Unknown
Socpus ID
84913549449 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/84913549449
STARS Citation
Williamson, Heather R.; Dow, Brian A.; and Davidson, Victor L., "Mechanisms For Control Of Biological Electron Transfer Reactions" (2014). Scopus Export 2010-2014. 9341.
https://stars.library.ucf.edu/scopus2010/9341