Title

A Series Of Fluorene-Based Two-Photon Absorbing Molecules: Synthesis, Linear And Nonlinear Characterization, And Bioimaging

Abstract

The synthesis, structural, and photophysical characterization of a series of new fluorescent donor-acceptor and acceptor-acceptor molecules, based on the fluorenyl ring system, with two-photon absorbing properties is described. These new compounds exhibited large Stokes shifts, high fluorescence quantum yields, and significantly, high two-photon absorption cross sections, making them well suited for two-photon fluorescence microscopy imaging. Confocal and two-photon fluorescence microscopy imaging of COS-7 and HCT 116 cells incubated with probe I showed endosomal selectivity, demonstrating the potential of this class of fluorescent probes in multiphoton fluorescence microscopy. © 2010 American Chemical Society.

Publication Date

6-18-2010

Publication Title

Journal of Organic Chemistry

Volume

75

Issue

12

Number of Pages

3975-3982

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1021/jo1005075

Socpus ID

77953511861 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/77953511861

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