Title

Timing Of Determining Axillary Lymph Node Status When Neoadjuvant Chemotherapy Is Used Topical Collection On Breast Cancer

Keywords

Adjuvant chemotherapy; Axillary lymph node status; Breast cancer; Neoadjuvant chemotherapy (NC); Sentinel lymph node biopsy before or after neoadjuvant chemotherapy

Abstract

Neoadjuvant chemotherapy is the standard of care for patients with locally advanced breast cancer and is a reasonable alternative to adjuvant chemotherapy for those with large operable disease. Potential clinical advantages of neoadjuvant chemotherapy include the conversion of some patients requiring mastectomy to candidates for breast-conserving surgery, the potential for downstaging axillary nodes and thus reducing the extent of axillary surgery, and the ability to correlate clinical and pathologic response to neoadjuvant chemotherapy with improved long-term outcomes. An important and controversial locoregional therapy issue in patients who are candidates for neoadjuvant chemotherapy relates to the timing of sentinel lymph node biopsy - i.e., either before or after neoadjuvant chemotherapy. This review will focus on the performance characteristics of sentinel lymph node biopsy before vs. after neoadjuvant chemotherapy and on the pros and cons of each approach. © 2014 Springer Science+Business Media New York.

Publication Date

1-1-2014

Publication Title

Current Oncology Reports

Volume

16

Issue

2

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/s11912-013-0364-y

Socpus ID

84899411116 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84899411116

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