Title

Effects Of Β-Hydroxy-Β-Methylbutyrate Free Acid And Cold Water Immersion On Post-Exercise Markers Of Muscle Damage

Keywords

C-reactive protein; Cryotherapy; Cytokines; HMB; Myoglobin; Recovery

Abstract

The aim of the current study was to examine the effects of cold water immersion (CWI) with and without the free acid form of β-hydroxy-β- methylbutyrate (HMB-FA) on markers of muscle damage following acute lower body resistance exercise. Forty recreationally resistance-trained men (22.3 ± 2.4 years) were randomly divided into one of the four groups: (1) Placebo (PL); (2) HMB-FA; (3) HMB-FA-CWI; (4) PL-CWI. HMB-FA groups ingested 3 g day -1 and CWI groups submersed their lower body into 10-12°C water for 10-min post-exercise. No differences between groups were observed for CK; however, PL-CWI had significantly greater elevations in myoglobin 30-min post-exercise compared to HMB-FA (p = 0.009) and PL (p = 0.005), and HMB-FA-CWI was significantly greater than HMB-FA (p = 0.046) and PL (p = 0.028). No differences between groups were observed for IL-6 and IL-10, although CRP was significantly greater 24-h post-exercise for PL-CWI compared to HMB-FA-CWI (p = 0.02) and HMB-FA (p = 0.046). Only HMB-FA-CWI showed significantly (p = 0.02) greater improvements in average power per repetition. CWI appeared to elevate myoglobin compared to other groups, while HMB-FA may have attenuated the increase in CRP when combined with CWI. Nevertheless, HMB-FA or CWI treatments did not appear to provide benefit over PL for recovery. Instead, the combination of CWI and HMB-FA improved performance recovery compared to other groups. © 2014 Springer-Verlag.

Publication Date

1-1-2014

Publication Title

Amino Acids

Volume

46

Issue

6

Number of Pages

1501-1511

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/s00726-014-1722-2

Socpus ID

84901393621 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84901393621

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