Miscarriage And Ectopic Pregnancy

Keywords

Differential diagnosis; Ectopic pregnancy; Local therapy; Medical management; Miscarriage; Obstetrics and Gynecology; Surgical treatment

Abstract

Vaginal bleeding during the first trimester of the pregnancy is one of the most common clinical scenarios encountered in Obstetrics and Gynecology, occurring in approximately one fourth of all pregnancies. The differential diagnosis of first trimester bleeding classically includes not only ectopic pregnancy (EP), but also miscarriage, and gestational trophoblastic disease. Miscarriage or spontaneous abortion is one of the most common complications of the pregnancy. Surgery is the definitive treatment of an ectopic pregnancy. Medical management of ectopic pregnancy, primarily with MTX (MTX), is a non‐invasive alternative to surgery. Ultrasound‐guided intra‐ectopic injection of MTX or other substances, including prostaglandins, potassium chloride, and hyperosmolar glucose have been described, usually with concurrent aspiration of the gestational sac, for the treatment of an ectopic pregnancy. Although the systemic administration of MTX is easier, local injection has been described in an effort to minimize the risk of systemic side effects.

Publication Date

1-1-2018

Publication Title

Evidence-based Obstetrics and Gynecology

Number of Pages

33-47

Document Type

Article; Book Chapter

Personal Identifier

scopus

DOI Link

https://doi.org/10.1002/9781119072980.ch4

Socpus ID

85101462212 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85101462212

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