Association Of Oxidative Stress And Lipids With Risk Factors Of Metabolic Syndrome

Abstract

The term “Metabolic Syndrome” (MS) refers to a group or cluster of risk factors, which together raise the risk of heart disease and related diseases, such as diabetes and stroke [1-3]. Recent advances seem to indicate that the definition may extend to other diseases, including colon cancer and other noncardiovascular diseases [4,5]. Thus, there is an increased awareness of the risk factors that may increase our propensity to acquire many different disease pathologies. The risk factors (Figure 17.1) that are typically thought about in the context of the MS are large waistline or waist circumference (WC), elevated plasma triglyceride (TG) levels, dysfunctional or low levels of high-density lipoprotein (HDL), high blood pressure (BP), higher plasma glucose (GL) levels, dysfunctional endothelium (DE), and inflammatory macrophages [6-12]. Family history of cardiovascular diseases, gender, race, ethnicity, dietary and nutritional factors, and other factors, including the use of certain drugs also may contribute to the profile of MS [13,14]. It is suggested that at least three metabolic risk factors be present to be diagnosed with MS.

Publication Date

1-1-2015

Publication Title

Lipid Oxidation in Health and Disease

Number of Pages

363-386

Document Type

Article; Book Chapter

Personal Identifier

scopus

DOI Link

https://doi.org/10.1201/b18138

Socpus ID

85054263434 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85054263434

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