Uric Acid As A Marker Of Kidney Disease: Review Of The Current Literature

Abstract

Uric acid has been implicated in the pathophysiology of renal disease; however renal clearance makes a causal relationship difficult to prove. We examine the current literature to support a potential role of uric acid in the development of kidney disease and to determine the potential to use uric acid as a marker for future renal decline. After review, we conclude that uric acid is definitively linked to the development of chronic kidney disease and can be a poor prognostic factor for the development of acute renal failure, as well. However, further human research is needed before predictive models utilizing uric acid can be developed and used in the clinical setting.

Publication Date

1-1-2015

Publication Title

Disease Markers

Volume

2015

Document Type

Editorial Material

Personal Identifier

scopus

DOI Link

https://doi.org/10.1155/2015/382918

Socpus ID

84935828007 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84935828007

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