Title
Synthesis And Antitubercular Activity Of 1,2,4-Trisubstitued Piperazines
Keywords
Antitubercular; Combinatorial chemistry; Solid phase synthesis; Substituted piperazines
Abstract
Parallel solid phase synthesis offers a unique opportunity for the synthesis and screening of large numbers of compounds and significantly enhances the prospect of finding new leads. We report the synthesis and antitubercular activity of chiral 1,2,4-trisubstituted piperazines derived from resin bound acylated dipeptides against Mycobacterium tuberculosis strain H37Rv.
Publication Date
5-1-2016
Publication Title
Bioorganic and Medicinal Chemistry Letters
Volume
26
Issue
9
Number of Pages
2206-2209
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1016/j.bmcl.2016.03.063
Copyright Status
Unknown
Socpus ID
84964039953 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/84964039953
STARS Citation
Rohde, Kyle H.; Michaels, Heather A.; and Nefzi, Adel, "Synthesis And Antitubercular Activity Of 1,2,4-Trisubstitued Piperazines" (2016). Scopus Export 2015-2019. 2898.
https://stars.library.ucf.edu/scopus2015/2898