Title

Small-Angle Scatter Tomography With A Photon-Counting Detector Array

Keywords

coherent scattering; dark-field; photon counting detectors; x-ray CT

Abstract

Small-angle x-ray scatter imaging has a high intrinsic contrast in cancer research and other applications, and provides information on molecular composition and micro-structure of the tissue. In general, the implementations of small-angle coherent scatter imaging can be divided into two main categories: direct tomography and angular dispersive computerized tomography. Based on the recent development of energy-discriminative photon-counting detector array, here we propose a computerized tomography setup based on energy-dispersive measurement with a photon-counting detector array. To show merits of the energy-dispersive approach, we have performed numerical tests with a phantom containing various tissue types, in comparison with the existing imaging approaches. The results show that with an energy resolution of ∼6 keV, the energy dispersive tomography system with a broadband tabletop x-ray would outperform the angular dispersive system, which makes the x-ray small-angle scatter tomography promising for high-specificity tissue imaging.

Publication Date

4-19-2016

Publication Title

Physics in Medicine and Biology

Volume

61

Issue

10

Number of Pages

3734-3748

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1088/0031-9155/61/10/3734

Socpus ID

84969560271 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84969560271

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