Small Caliber Covered Self-Expanding Metal Stents In The Management Of Malignant Dysphagia

Keywords

Dysphagia; Esophageal cancer; Esophageal stent

Abstract

Background: Use of large caliber [≥18 mm body diameter (BD)] self-expanding metal stents (SEMS) for management of malignant dysphasia is associated with substantial adverse event (AE) and mortality rates (MRs). We sought to determine dysphagia response, stent migration rates, and AE and MRs, for small caliber covered SEMS (sccSEMS) with BDs between 10-16 mm in malignant dysphagia. Methods: Thirty-one patients underwent direct endoscopic placement of 50 sccSEMS between January 2008 and March 2011. Patients were monitored for change in dysphagia score (DS), stent migration, AEs, and death through May 2011. Results: DS improved in 30 of 31 patients (97%). The median DS decreased from 3 to 2 (P < 0.0001). The median effective duration of first sccSEMS placement was 116 (95% CI: 75-196) days. Major and minor AE rates were 6.5% and 19.4% respectively. No stent related deaths were encountered. The overall migration rate was 36% (18/50). The anticipated migration rate was 45.7% (16/35) and the unanticipated migration rate was 13.3% (2/15) (P=0.052). Positive effective clinical outcome occurred in 93.5% (29/31) of cases. Conclusions: In malignant dysphagia, direct endoscopic sccSEMS placement provided acceptable dysphagia control and migration rates with substantial reductions in stent related AEs and MRs compared to those reported for large caliber SEMS.

Publication Date

6-1-2016

Publication Title

Journal of Gastrointestinal Oncology

Volume

7

Issue

3

Number of Pages

411-419

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.21037/jgo.2015.12.03

Socpus ID

84995752867 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84995752867

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