Evaluation Of A New Software Version Of The Rtvue Optical Coherence Tomograph For Image Segmentation And Detection Of Glaucoma In High Myopia

Keywords

ganglion cell complex; high myopia; retinal nerve fiber layer thickness; RTVue-100 Fourier-domain optical coherence tomograph

Abstract

Purpose: To compare the current (6.3) and a novel software version (6.12) of the RTVue-100 optical coherence tomograph (RTVue-OCT) for ganglion cell complex (GCC) and retinal nerve fiber layer thickness (RNFLT) image segmentation and detection of glaucoma in high myopia. Materials and Methods: RNFLT and GCC scans were acquired with software version 6.3 of the RTVue-OCT on 51 highly myopic eyes (spherical refractive error ≤-6.0 D) of 51 patients, and were analyzed with both the software versions. Twenty-two eyes were nonglaucomatous, 13 were ocular hypertensive and 16 eyes had glaucoma. Results: No difference was seen for any RNFLT, and average GCC parameter between the software versions (paired t test, P≥0.084). Global loss volume was significantly lower (more normal) with version 6.12 than with version 6.3 (Wilcoxon signed-rank test, P<0.001). The percentage agreement (κ) between the clinical (normal and ocular hypertensive vs. glaucoma) and the software-provided classifications (normal and borderline vs. outside normal limits) were 0.3219 and 0.4442 for average RNFLT, and 0.2926 and 0.4977 for average GCC with versions 1 and 2, respectively (McNemar symmetry test, P≥0.289). No difference in average RNFLT and GCC classification (McNemar symmetry test, P≥0.727) and the number of eyes with at least 1 segmentation error (P≥0.109) was found between the software versions, respectively. Conclusion: Although GCC segmentation was improved with software version 6.12 compared with the current version in highly myopic eyes, this did not result in a significant change of the average RNFLT and GCC values, and did not significantly improve the software-provided classification for glaucoma.

Publication Date

1-1-2016

Publication Title

Journal of Glaucoma

Volume

25

Issue

6

Number of Pages

e615-e619

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1097/IJG.0000000000000290

Socpus ID

84975295470 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84975295470

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