Falling Under The Umbrella Cells: A Single Institutional Experience And Literature Review Of Urothelial Carcinoma Presenting As A Primary Pancreatic Mass On Endoscopic Ultrasound-Guided Fine-Needle Aspiration

Keywords

Endoscopic ultrasound-guided fine-needle aspiration; pancreatic metastases; rapid on-site evaluation; urothelial carcinoma

Abstract

Metastases to the pancreas are much less common than primary pancreatic lesions, and there are few reports in the literature of metastatic urothelial carcinoma (UC) found in the pancreas. We report two cases of metastatic UC mimicking a primary pancreatic lesion. Two female patients, aged 48 and 83 years, presented with isolated pancreatic lesions causing obstructive jaundice suspicious for pancreatic adenocarcinoma and underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) with rapid on-site evaluation (ROSE). On cytopathology, the lesions were found to be UC, confirmed with immunohistochemical (IHC) staining. UC rarely metastasizes to the pancreas, and diagnosis through EUS-FNA can be challenging. However, the utilization of ROSE, dedicated cell block passes, and IHC have proved to be effective in obtaining this unusual pancreatic diagnosis by EUS-FNA.

Publication Date

1-1-2017

Publication Title

CytoJournal

Volume

14

Issue

1

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.4103/1742-6413.202601

Socpus ID

85018470722 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85018470722

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