Title

Selective Nano-Sensing Approach For The Determination Of Inorganic Phosphate In Human Urine Samples

Keywords

FRET; Gold nanoparticles; Lanthanide sensor; Lifetime analysis; Phosphate ions; Urine analysis

Abstract

A novel sensing approach is presented for the analysis of phosphate ions in human urine samples. The new sensor is based on the fluorescence energy transfer between a luminescent probe ([Tb-EDTA]−1) and gold nanoparticles capped with a cetyltrimethylammonium bromide (Au NPs-CTAB). The strong affinity between CTAB receptors and phosphate ions results in a highly selective assay with minimum sample preparation steps. Possible chemical interference is monitored on real-time basis via luminescence lifetime analysis. The simplicity of analysis and the competitive limit of detection in the micro-molar concentration range provide a well-suited approach for routine monitoring of phosphate ions in numerous urine samples.

Publication Date

3-1-2017

Publication Title

Talanta

Volume

164

Number of Pages

209-215

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.talanta.2016.11.017

Socpus ID

85000819106 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85000819106

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