¹⁸F-Naf Pet/Ct In Extensive Melorheostosis Of The Axial And Appendicular Skeleton With Soft-Tissue Involvement

Creator

Georgios Z. Papadakis, NIH Clinical Center (CC)
Smita Jha, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Timothy Bhattacharyya, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Corina Millo, National Institutes of Health (NIH)
Tsang Wei Tu, NIH Clinical Center (CC)

Keywords

18 F-NaF PET/CT; Bone dysplasia; Melorheostosis; Osteosclerosis; Soft-tissue ossified masses

Abstract

Melorheostosis is a rare, nonhereditary, benign, sclerotic bone dysplasia with no sex predilection, typically occurring in late childhood or early adulthood, which can lead to substantial functional morbidity, depending on the sites of involvement. We report on a patient with extensive melorheostosis in the axial and appendicular skeleton, as well as in the soft tissues, who was evaluated with whole-body 18F-NaF PET/CT scan. All melorheostotic lesions of the skeleton and of the ossified soft-tissue masses demonstrated intensely increased 18F-NaF activity, suggesting the application of this modality in assessing and monitoring the disease activity.

Publication Date

3-17-2017

Publication Title

Clinical Nuclear Medicine

Volume

42

Issue

7

Number of Pages

537-539

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1097/RLU.0000000000001647

Copyright Status

Unknown

Socpus ID

85015653375 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85015653375

STARS Citation

Papadakis, Georgios Z.; Jha, Smita; Bhattacharyya, Timothy; Millo, Corina; and Tu, Tsang Wei, "¹⁸F-Naf Pet/Ct In Extensive Melorheostosis Of The Axial And Appendicular Skeleton With Soft-Tissue Involvement" (2017). Scopus Export 2015-2019. 5985.
https://stars.library.ucf.edu/scopus2015/5985