Solid-Liquid Phase Change Nanoparticles As Thermally Addressable Biosensors

Abstract

A challenge of turning molecular biology knowledge into advance in disease detection to benefit patients is that most of available biomarkers are not powerful, lacking either sensitivity or specificity. Parallel to the effort of finding more specific biomarkers, one feasible way of providing better predictive value is to detect multiple low specificity biomarkers, and collectively analyze the response of multiple biomarkers contained in a sample. The multiplexed detection can enhance the reliability and reduce the number of invasive and painful biopsies. In addition, the concentrations of biomarkers can vary several orders of magnitude. Thereby an ideal detection should be able to detect biomarkers with high sensitivity and high multiplicity.

Publication Date

1-1-2017

Publication Title

Biosensors Based on Nanomaterials and Nanodevices

Number of Pages

433-442

Document Type

Article; Book Chapter

Personal Identifier

scopus

DOI Link

https://doi.org/10.1201/b16234

Socpus ID

85054248130 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85054248130

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