Effects Of Time-Release Caffeine Containing Supplement On Metabolic Rate, Glycerol Concentration And Performance

Keywords

Caffeine bioavailability; Energy; Multiple object tracking; Pharmacokinetics; Reaction time; Sustained release caffeine

Abstract

This study compared caffeine pharmacokinetics, glycerol concentrations, metabolic rate, and performance measures following ingestion of a time-release caffeine containing supplement (TRCAF) versus a regular caffeine capsule (CAF) and a placebo (PL). Following a double-blind, placebo-controlled, randomized, cross-over design, ten males (25.9 ± 3.2 y) who regularly consume caffeine ingested capsules containing either TR-CAF, CAF, or PL. Blood draws and performance measures occurred at every hour over an 8-hour period. Plasma caffeine concentrations were significantly greater (p < 0.05) in CAF compared to TR-CAF during hours 2-5 and significantly greater (p = 0.042) in TR-CAF compared to CAF at hour 8. There were no significant differences between trials in glycerol concentrations (p = 0.86) or metabolic measures (p = 0.17-0.91). Physical reaction time was significantly improved for CAF at hour 5 (p=0.01) compared to PL. Average upper body reaction time was significantly improved for CAF and TR-CAF during hours 1-4 (p = 0.04 and p = 0.01, respectively) and over the 8-hour period (p = 0.04 and p = 0.001, respectively) compared to PL. Average upper body reaction time was also significantly improved for TR-CAF compared to PL during hours 5-8 (p = 0.004). TR-CAF and CAF showed distinct pharmacokinetics yielding modest effects on reaction time, yet did not alter glycerol concentration, metabolic measures, or other performance measures.

Publication Date

1-1-2015

Publication Title

Journal of Sports Science and Medicine

Volume

14

Issue

2

Number of Pages

322-332

Document Type

Article

Personal Identifier

scopus

Socpus ID

84928988104 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84928988104

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