Perioperative Management Of Paediatric Patients With Sickle Cell Disease

Keywords

Paediatric patients; Perioperative management; Sickle cell disease

Abstract

Patients with sickle cell disease (SCD) are prone to acute and chronic organ injuries that may necessitate surgical interventions earlier and with more frequency than non-SCD cohorts. They are also at an increased risk for perioperative morbidity and mortality because of the inherent pathophysiological derangements associated with SCD. Perioperative outcomes are influenced by phenotype variability, end-organ injury and the variable risks of surgical procedures, as well as the availability of beneficial therapies, especially where resources may be limited. Safe and effective perioperative management relies on anticipation and avoidance of complications, which can be best achieved by collaboration among anaesthesiologists, intensivists, surgeons and haematologists. This review addresses potential perioperative complications and contemporary management to assist in the perioperative care of paediatric patients with SCD.

Publication Date

1-1-2017

Publication Title

West Indian Medical Journal

Volume

66

Issue

4

Number of Pages

469-477

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.7727/wimj.2017.135

Socpus ID

85035788592 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85035788592

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