Oral Lichen Sclerosus—A Review Of Clinical Presentation, Treatment, And Clinical Outcomes

Abstract

Objective: The aim of this study was to evaluate the disease involvement, treatment and response, and malignant potential of oral lichen sclerosus (LS). Study Design: We conducted a review of the literature of 37 cases of oral LS. We looked specifically for the following data: patient demographic characteristics, disease involvement, treatment, response to treatment, duration of follow-up, symptoms, risk factors for oral malignancy, and malignant transformation. Results: The most common area of oral involvement included the labial mucosa (67.6%). Of patients with oral LS, 38.5% reported symptoms, and 35.1% exhibited extraoral manifestations. Patients were less likely to receive treatment when asymptomatic (62.5%) than when symptomatic (80%). Topical steroids were more efficacious (66.7%) compared with other treatments. Risk factors for malignancy were found in 25% of patients. No patient had malignant transformation of oral lesions at follow-up (mean follow-up 22.1 months; median 12 months). Conclusions: More data and longer follow-up are required to determine the long-term clinical outcomes of oral LS.

Publication Date

10-1-2017

Publication Title

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Volume

124

Issue

4

Number of Pages

e243-e248

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.oooo.2017.07.005

Socpus ID

85028539171 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85028539171

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