Design And Development Of A Magnetically-Driven Ventricular Assist Device (Mvad): In Vitro Implementation In The Fontan Circulation

Keywords

Applications; Computing methods; Coupled problems; Instructions; Multiphysics problems

Abstract

A rapidly testable novel Magnetically-Driven Ventricular Assist Device (MVAD) with no moving parts that can be used to provide assistance to the cardiovascular circulation while reducing caval pressure in patients who have undergone the Fontan procedure to palliate the Hypoplastic Left Heart Syndrome (HLHS) is proposed and studied. A benchtop Mock Flow Loop (MFL) of the cardiovascular circulation with a Fontan total cavopulmonary connection (TCPC) is configured to validate this hypothesis. The MFL is based on a Lumped-Parameter Model (LPM) comprised of upper and lower systemic circulation as well as left and right pulmonary circulation compartments. Needle valves are used to accurately replicate vascular resistance (R) while compliance chambers are used to mimic vascular compliance (C). The MFL centerpiece is the truncated aortic arch with an implanted MVAD. A ferro-fluid solution is mixed in water to simulate magnetically-charged blood. The pulsating flow is induced by drawing the ferro-fluid from a main reservoir with a Harvard Apparatus Medical pump while the MVAD provides assistive momentum to the TCPC. Flow and pressure sensor data at specific points in the MFL are acquired via a National Instruments multichannel data acquisition board and processed using LabView. Different prototypes of the MVAD are tested to validate the hypothesis.

Publication Date

1-1-2017

Publication Title

Proceedings of the 7th International Conference on Coupled Problems in Science and Engineering, COUPLED PROBLEMS 2017

Volume

2017-January

Number of Pages

482-490

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

Socpus ID

85045338400 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85045338400

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