Title

Eosinophilic Angiocentric Fibrosis: A Sino-Orbital Masquerader

Keywords

ophthalmology; rheumatology

Abstract

A 58-year-old Caucasian male presented with left periorbital oedema extending to the nasal area for 1 year along with nasal discharge for 1 month. Lab work was significant for positive cytoplasmic antineutrophil cytoplasmic antibodies. CT scan showed solid mass along the nasal soft tissue with bony nasal destruction. A CT scan of the thorax was performed to rule out granulomatosis with polyangiitis and showed multiple pulmonary nodules. Biopsies of the nasal mass and lung nodule were performed which showed fragments of fibrosis with spindle cell proliferation consistent with eosinophilic angiocentric fibrosis (EAF). EAF is a very rare disease, recently described as a subtype of immunoglobulin G4-related disease. A few rare cases of EAF involving the structures of the orbit have been reported in the literature.

Publication Date

1-1-2018

Publication Title

BMJ Case Reports

Volume

2018

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1136/bcr-2017-223675

Socpus ID

85051398071 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85051398071

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