Super-Absorbent Polymer Valves And Colorimetric Chemistries For Time-Sequenced Discrete Sampling And Chloride Analysis Of Sweat Via Skin-Mounted Soft Microfluidics

Keywords

microfluidics; perspiration; super absorbent polymer; sweat chloride

Abstract

This paper introduces super absorbent polymer valves and colorimetric sensing reagents as enabling components of soft, skin-mounted microfluidic devices designed to capture, store, and chemically analyze sweat released from eccrine glands. The valving technology enables robust means for guiding the flow of sweat from an inlet location into a collection of isolated reservoirs, in a well-defined sequence. Analysis in these reservoirs involves a color responsive indicator of chloride concentration with a formulation tailored to offer stable operation with sensitivity optimized for the relevant physiological range. Evaluations on human subjects with comparisons against ex situ analysis illustrate the practical utility of these advances.

Publication Date

3-22-2018

Publication Title

Small

Volume

14

Issue

12

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1002/smll.201703334

Socpus ID

85041286853 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85041286853

This document is currently not available here.

Share

COinS