Title

Fructose-Containing Sugars And Cardiovascular Disease

Keywords

Fructose; High-fructose corn sugar; Metabolism; Sucrose; Sugars

Abstract

Cardiovascular disease (CVD) is the single largest cause of mortality in the United States and worldwide. Numerous risk factors have been identified for CVD, including a number of nutritional factors. Recently, attention has been focused on fructose-containing sugars and their putative link to risk factors for CVD. In this review, we focus on recent studies related to sugar consumption and cardiovascular risk factors including lipids, blood pressure, obesity, insulin resistance, diabetes, and the metabolic syndrome. We then examine the scientific basis for competing recommendations for sugar intake. We conclude that although it appears prudent to avoid excessive consumption of fructose- containing sugars, levels within the normal range of human consumption are not uniquely related to CVD risk factors with the exception of triglycerides, which may rise when simple sugars exceed 20% of energy per day, particularly in hypercaloric settings.

Publication Date

1-1-2015

Publication Title

Advances in Nutrition

Volume

6

Issue

4

Number of Pages

430-439

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.3945/an.114.008177

Socpus ID

84953401895 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84953401895

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