Computational Analysis Of Inspiratory And Expiratory Flow In The Lung Airway

Keywords

Airways; Computational Fluid Dynamics; Pig lung; Pressure loss

Abstract

Inspiratory and expiratory flow in a multi-generation pig lung airway was numerically studied at a peak tracheal flow rate corresponding to a Reynolds number of 1150. The model was validated by comparing velocity distributions with previous measurements for a simple airway bifurcation. Simulation results at different cross sections of the airway tree provided detailed maps of the axial and secondary flow patterns. Flow at the main bifurcation and in many other bifurcations showed complex secondary flow structures. The flow morphology in the pig airways differed from that of simplified bifurcation airway models and that of humans, which is likely due to the large differences in the airway geometry of the different species. The inspiratory pressure drop was calculated, and simulation results suggested that the viscous pressure drop values were comparable to earlier studies in human airway geometries. The reported differences between pig and human airways need to be taken into consideration when generalizing results of animal experiments to humans.

Publication Date

1-1-2018

Publication Title

Proceedings of the Thermal and Fluids Engineering Summer Conference

Volume

2018-March

Number of Pages

1083-1086

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

DOI Link

https://doi.org/10.1615/TFEC2018.bio.021629

Socpus ID

85056184918 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85056184918

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