Title

Pulsatile Multi-Scale Fluid Structure Interaction Modeling For Optimal Left Ventricular Assist Device Implantation

Keywords

Computational Fluid Dynamics; Finite Element Analysis; Fluid-Structure Interaction; Left Ventricular Assist Device; Multi-scale

Abstract

A Left Ventricular Assist Device (LVAD), is a mechanical pump designed to supplement circulatory requirements and reduce the workload of a failing heart, allowing for partial recovery of myocardial functionality as well as a destination therapy. Despite improvements in device design and anticoagulation treatment, VADs have a 20% to 40% chance of causing a thrombo-embolism event after 6 months. Stroke incidence can be significantly reduced by adjusting the VAD outflow cannula to direct particles away from the cerebral vessels. In this study, we build upon our previous work that generated a time-dependent multi-scale CFD analysis of patient-specific geometry models of the VAD-bed vasculature and combine it with a Finite Element Analysis (FEA) to account for vessel compliance, generating a Fluid Structure Interaction (FSI) to further explore this hypothesis.

Publication Date

1-1-2018

Publication Title

Proceedings of the Thermal and Fluids Engineering Summer Conference

Volume

2018-March

Number of Pages

1145-1154

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

DOI Link

https://doi.org/10.1615/TFEC2018.bio.024758

Socpus ID

85090763066 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85090763066

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