Fabrication And Characterization Of 3D Printed, 3D Microelectrode Arrays With Spin Coated Insulation And Functional Electrospun 3D Scaffolds For “Disease In A Dish” And “Organ On A Chip” Models
Abstract
We demonstrate a new fabrication technology for 3D Microelectrode Arrays (MEAs) to stimulate and record electrophysiological activity from cellular networks in-vitro. Electrospun Polyethylene Terephthalate (PET) 3D scaffolds are coupled to the fabricated MEAs which make them fully functional for “disease in a dish” and “organ on a chip” models to promote cell/tissue growth and regeneration. The microfabrication technology involves 3D towers realized by 3D printing and a metallization layer, defined by stencil mask evaporation techniques. Multiple insulation strategies are reported: a drop-casted/spin-coated 3D layer of Polystyrene (PS) and an evaporated layer of SiO2, both of which are laser micromachined to realize the 3D microelectrodes.
Publication Date
1-1-2018
Publication Title
2018 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2018
Number of Pages
124-127
Document Type
Article; Proceedings Paper
Personal Identifier
scopus
DOI Link
https://doi.org/10.31438/trf.hh2018.36
Copyright Status
Unknown
Socpus ID
85070334960 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/85070334960
STARS Citation
Azim, Nilab; Ausaf, Tariq; Kundu, Avra; Zhai, Lei; and Rajaraman, Swaminathan, "Fabrication And Characterization Of 3D Printed, 3D Microelectrode Arrays With Spin Coated Insulation And Functional Electrospun 3D Scaffolds For “Disease In A Dish” And “Organ On A Chip” Models" (2018). Scopus Export 2015-2019. 8898.
https://stars.library.ucf.edu/scopus2015/8898
