Title

Fabrication And Characterization Of 3D Printed, 3D Microelectrode Arrays With Spin Coated Insulation And Functional Electrospun 3D Scaffolds For “Disease In A Dish” And “Organ On A Chip” Models

Abstract

We demonstrate a new fabrication technology for 3D Microelectrode Arrays (MEAs) to stimulate and record electrophysiological activity from cellular networks in-vitro. Electrospun Polyethylene Terephthalate (PET) 3D scaffolds are coupled to the fabricated MEAs which make them fully functional for “disease in a dish” and “organ on a chip” models to promote cell/tissue growth and regeneration. The microfabrication technology involves 3D towers realized by 3D printing and a metallization layer, defined by stencil mask evaporation techniques. Multiple insulation strategies are reported: a drop-casted/spin-coated 3D layer of Polystyrene (PS) and an evaporated layer of SiO2, both of which are laser micromachined to realize the 3D microelectrodes.

Publication Date

1-1-2018

Publication Title

2018 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2018

Number of Pages

124-127

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

DOI Link

https://doi.org/10.31438/trf.hh2018.36

Socpus ID

85070334960 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85070334960

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