Keywords

meta-analysis, MDMA, ecstasy, cognitive functioning

Abstract

Studies using animal models have found considerable evidence of neurological damage resulting from exposure to 3,4- methylenedioxymethamphetamine (MDMA, ecstasy). Yet, studies comparing the cognitive performance of human recreational ecstasy users to ecstasy naïve controls have produced inconsistent results. The present study is a meta-analysis of the published empirical literature on the cognitive sequelae of human recreational ecstasy use. The pooled effect size estimate for combined cognitive domains was statistically significant and moderate in size. Small to large, statistically significant aggregate effect sizes resulted for eight of the nine cognitive ability domains included in the analysis. Moderator analyses suggested that frequent ecstasy use is associated with greater cognitive impairment, cognitive impairment can occur after relatively low amounts of total lifetime cumulative use, and recovery of functioning does not occur within one year post cessation.

Notes

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Graduation Date

2005

Semester

Summer

Advisor

Dunn, Michael

Degree

Doctor of Philosophy (Ph.D.)

College

College of Arts and Sciences

Department

Psychology

Degree Program

Psychology

Format

application/pdf

Identifier

CFE0000701

URL

http://purl.fcla.edu/fcla/etd/CFE0000701

Language

English

Release Date

August 2008

Length of Campus-only Access

None

Access Status

Doctoral Dissertation (Open Access)

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Included in

Psychology Commons

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