Abstract

Ginger (Zingiber Officinale) has been used in Asia for centuries to treat various ailments. Ginger has been reported to alleviate migraine pain via four bioactive compounds that can reduce nitric oxide synthase (NOS) resulting in the inhibition of nitric oxide (NO). The inhibition of nitric oxide results in the vasoconstriction of the intracranial blood vessels alleviating migraine pain. It is hypothesized that ginger has structural similarities to vasoconstrictor drugs causing similar receptor interactions. A review of the bioactive compounds in ginger and popular vasoconstrictor drugs was done to determine structural similarities. The results of this study show that the compounds in ginger share no structural similarities with vasoconstrictor drugs used in the treatment of migraine headaches.

Thesis Completion

2017

Semester

Fall

Thesis Chair

Elsheimer, Seth

Co-Chair

Samsam, Mohtashem

Degree

Bachelor of Science (B.S.)

College

College of Sciences

Department

Chemistry

Degree Program

Biochemistry

Location

Orlando (Main) Campus

Language

English

Access Status

Open Access

Release Date

1-15-2017

Share

COinS