Abstract
A major challenge in the Computational Fluid Dynamics (CFD) modeling of the human respiratory system is the complex variation of geometric scale from the trachea to the peripheral airways. The current literature on image-based lung flow analysis is limited to a few (typically 5) generations beyond the trachea. Such studies, which are limited largely by computational intensity and computational cost, also have limited accuracy. In this study we propose a hybrid methodology that enables CFD analysis from the middle to the distal airways through to the alveolar level. A hybrid lung model is generated where the middle airways are reconstructed from human CT-scans using open-source image analysis and extended to distal parts utilizing a section of airway branching tree generated based on deterministic algorithm. Such hybrid models allow the application of physiologically relevant boundary conditions instead of the approximation methods often used in previous studies in the region of interest. Two different breathing conditions are investigated, and the results are validated by comparison with previous experimental and numerical data.
Notes
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Graduation Date
2022
Semester
Summer
Advisor
Ilegbusi, Olusegun
Degree
Master of Science in Mechanical Engineering (M.S.M.E.)
College
College of Engineering and Computer Science
Department
Mechanical and Aerospace Engineering
Degree Program
Mechanical Engineering; Mechanical Systems
Identifier
CFE0009194; DP0026790
URL
https://purls.library.ucf.edu/go/DP0026790
Language
English
Release Date
August 2023
Length of Campus-only Access
1 year
Access Status
Masters Thesis (Open Access)
STARS Citation
Islam, Adnan, "Computational Modeling of Respiratory Airflow in Human Distal Airways Using Hybrid Lung Model" (2022). Electronic Theses and Dissertations, 2020-2023. 1223.
https://stars.library.ucf.edu/etd2020/1223