Keywords
microgravity, microfluidics, CFD, microfluidic device, osteoporosis
Abstract
In recent years, space exploration has been driving studies that enable sustained human presence in space. In such studies, fluidics relating to biology have become important. Fluids in biological systems span from large-scale flows relevant to circulatory, digestion, and pulmonary systems, but also involve many micro-scale porous flows. Hence, space exploration is driving a novel need to characterize fluidics in microscales in microgravity conditions. In this work, we study the porous flow network within bones that stimulates cellular growth and has the potential to relate to osteoporosis (including driving osteoporosis in astronauts). To study this effect, computational fluid dynamics (CFD) simulations are performed on a microfluidic device with a hexagon structure and compared to experimental results in both normal gravity (1g) and microgravity (0g) via Blue Origin's New Shepard Vehicle (NS-23 attempt and NS-24 launch). CFD results have been created to predict the transport character of nutrients in the bones. These insights have the potential to lead to preventative measures for osteoporosis in astronauts.
Completion Date
2024
Semester
Summer
Committee Chair
Kinzel, Michael
Degree
Master of Science in Aerospace Engineering (M.S.A.E.)
College
College of Engineering and Computer Science
Department
Mechanical and Aerospace Engineering
Degree Program
Aerospace Engineering
Format
application/pdf
Identifier
DP0028495
URL
https://purls.library.ucf.edu/go/DP0028495
Language
English
Release Date
8-15-2024
Length of Campus-only Access
None
Access Status
Masters Thesis (Open Access)
Campus Location
Orlando (Main) Campus
STARS Citation
Peterson, Taylor A., "A Study of the Effects of Microgravity Through Porous Media in Microfluidic Devices" (2024). Graduate Thesis and Dissertation 2023-2024. 290.
https://stars.library.ucf.edu/etd2023/290
Accessibility Status
Meets minimum standards for ETDs/HUTs