Title
Drug/Dye-Loaded, Multifunctional Iron Oxide Nanoparticles for Combined Targeted Cancer Therapy and Dual Optical/Magnetic Resonance Imaging
Abbreviated Journal Title
Small
Keywords
click chemistry; drug delivery; magnetic materials; magnetic resonance; imaging; IN-VIVO; MAGNETIC NANOPARTICLES; CLICK CHEMISTRY; CELLS; DELIVERY; PROBE; VITRO; Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience &; Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter
Abstract
A biocompatible, multimodal, and theranostic functional iron oxide nanoparticle is synthesized using a novel water-based method and exerts excellent properties for targeted cancer therapy, and optical and magnetic resonance imaging. For the first time, a facile, modified solvent diffusion method is used for the co-encapsulation of both. an anticancer drug and near-infrared dyes. The resulting folate-derivatized theranostics nanoparticles could allow for targeted optical/magnetic resonance imaging and targeted killing of folate-expressing cancer cells.
Journal Title
Small
Volume
5
Issue/Number
16
Publication Date
1-1-2009
Document Type
Article
Language
English
First Page
1862
Last Page
1868
WOS Identifier
ISSN
1613-6810
Recommended Citation
"Drug/Dye-Loaded, Multifunctional Iron Oxide Nanoparticles for Combined Targeted Cancer Therapy and Dual Optical/Magnetic Resonance Imaging" (2009). Faculty Bibliography 2000s. 2091.
https://stars.library.ucf.edu/facultybib2000/2091