Antithrombin activity of some constituents from Origanum vulgare

    Authors

    E. Goun; G. Cunningham; S. Solodnikov; O. Krasnykch;H. Miles

    Abbreviated Journal Title

    Fitoterapia

    Keywords

    Origanum vulgare; aristolochic acid I and II; D-(+)-raffinose; antithrombin activity; anticancer activity; Chemistry, Medicinal; Pharmacology & Pharmacy

    Abstract

    Aristolochic acid I, aristolochic acid II and D-(+)-raffinose were isolated from Origanum vulgare. Their inhibition of thrombin and activity against leukemia were evaluated. Aristolochic acid I and II have high inhibition of thrombin activity and were confirmed to possess activity against cancer. (C) 2002 Elsevier Science B.V. All rights reserved.

    Journal Title

    Fitoterapia

    Volume

    73

    Issue/Number

    7-8

    Publication Date

    1-1-2002

    Document Type

    Article

    Language

    English

    First Page

    692

    Last Page

    694

    WOS Identifier

    WOS:000179933400021

    ISSN

    0367-326X

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