Title

Antithrombin activity of some constituents from Origanum vulgare

Authors

Authors

E. Goun; G. Cunningham; S. Solodnikov; O. Krasnykch;H. Miles

Abbreviated Journal Title

Fitoterapia

Keywords

Origanum vulgare; aristolochic acid I and II; D-(+)-raffinose; antithrombin activity; anticancer activity; Chemistry, Medicinal; Pharmacology & Pharmacy

Abstract

Aristolochic acid I, aristolochic acid II and D-(+)-raffinose were isolated from Origanum vulgare. Their inhibition of thrombin and activity against leukemia were evaluated. Aristolochic acid I and II have high inhibition of thrombin activity and were confirmed to possess activity against cancer. (C) 2002 Elsevier Science B.V. All rights reserved.

Journal Title

Fitoterapia

Volume

73

Issue/Number

7-8

Publication Date

1-1-2002

Document Type

Article

Language

English

First Page

692

Last Page

694

WOS Identifier

WOS:000179933400021

ISSN

0367-326X

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