Development of a laser plasma x-ray microscope to observe live hydrated biological specimens

    Authors

    M. Kado; H. Daido; Y. Yamamoto; K. Shinohara;M. C. Richardson

    Comments

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    Abbreviated Journal Title

    Laser Phys. Lett.

    Keywords

    live hydrated specimens; laser plasma x ray; contact x-ray microscopy; functional structure; in vivo observation; MICROGRAPHY; Instruments & Instrumentation

    Abstract

    Investigating the structure and the function of life object performing advanced life activity becomes important. In order to investigate the life object, it is necessary to observe living specimens with high spatial resolution and high temporal resolution. Since laser plasma x-ray source has high brightness and short pulse duration, x-ray microscope with the laser plasma x-ray source makes possible to observe living specimens. Such as chromosomes, macrophages, bacterium, and so on have been observed by contact x-ray microscopy. The x-ray images obtained by indirect measurements such as the contact x-ray microscopy have difficulty to avoid artificial effect such as irregular due to developing process. Development of an x-ray microscope with laser plasma x-ray source is necessary to avoid such defects. We have been developing an x-ray microscope with laser plasma xray source to observe wet live specimens. The detail of the x-ray microscope will be presented.

    Journal Title

    Laser Physics Letters

    Volume

    3

    Issue/Number

    4

    Publication Date

    1-1-2006

    Document Type

    Article

    Language

    English

    First Page

    205

    Last Page

    207

    WOS Identifier

    WOS:000236692900008

    ISSN

    1612-2011

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