Title

Antimicrobial peptide microbicides targeting HIV

Authors

Authors

A. M. Cole

Comments

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Abbreviated Journal Title

Protein Pept. Lett.

Keywords

antimicrobial; peptide; defensin; HIV-1; cathelicidin; human; minidefensin; STD; HUMAN-IMMUNODEFICIENCY-VIRUS; RHESUS-MACAQUE LEUKOCYTES; HOST-DEFENSE; ALPHA-DEFENSINS; INNATE IMMUNITY; BETA-DEFENSIN; BACTERICIDAL ACTIVITY; CHASSALIA-PARVIFOLIA; TOPICAL MICROBICIDES; ANTI-HIV-1 ACTIVITY; Biochemistry & Molecular Biology

Abstract

Cationic antimicrobial peptides and proteins are among the earliest molecular effectors of the innate arm of immunity in humans and other vertebrates. This review, inspired by recent emphasis on the development of topical preventatives for sexually transmitted infections, describes antimicrobial peptides and proteins in the context of microbicide design and development. Particular emphasis is placed on the defensin family of peptides.

Journal Title

Protein and Peptide Letters

Volume

12

Issue/Number

1

Publication Date

1-1-2005

Document Type

Article

Language

English

First Page

41

Last Page

47

WOS Identifier

WOS:000226057400008

ISSN

0929-8665

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