Title

One-step, nanoparticle-mediated bacterial detection with magnetic relaxation

Authors

Authors

C. Kaittanis; S. A. Naser;J. M. Perez

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Nano Lett.

Keywords

AVIUM SUBSPECIES PARATUBERCULOSIS; CROHNS-DISEASE; MYCOBACTERIUM-PARATUBERCULOSIS; IDENTIFICATION; PROBES; Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience &; Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter

Abstract

Acknowledging the need for the development of fast and sensitive bacterial detection methods, we functionalized superparamagnetic iron oxide nanoparticles to identify Mycobacterium avium spp. paratuberculosis (MAP), through magnetic relaxation. Our results indicate that the MAP nanoprobes (1) bind specifically to MAP, (2) can quantify the bacterial target quickly in milk and blood with high sensitivity, and (3) are not susceptible to interferences caused by other bacteria. The use of the described magnetic nanosensors in the identification and quantification of bacteria in clinical and environmental samples is anticipated.

Journal Title

Nano Letters

Volume

7

Issue/Number

2

Publication Date

1-1-2007

Document Type

Article

Language

English

First Page

380

Last Page

383

WOS Identifier

WOS:000244206500029

ISSN

1530-6984

Share

COinS