Title

Inner Filter Effect on Surface Enhanced Raman Spectroscopic Measurement

Authors

Authors

F. S. Ameer; S. M. Ansar; W. F. Hu; S. L. Zou;D. M. Zhang

Comments

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Abbreviated Journal Title

Anal. Chem.

Keywords

GOLD NANOPARTICLE; SCATTERING SERS; HOT-SPOTS; SILVER; FLUORESCENCE; MOLECULE; CLUSTERS; DIMERS; FILM; Chemistry, Analytical

Abstract

Presented herein is a combined experimental and computational study of the gold nanopartide (AuNP) inner filter effect on surface enhanced Raman spectroscopic (SERS) measurements. Using a bianalyte strategy in which dithiopurine (DTP) and ethanol were employed as the model analytes, we demonstrated that AuNPs enhance DTP's Raman signal but attenuate ethanol's Raman intensity. Combined time-resolved UV-vis and Raman measurements showed that AuNP aggregation has significant and an exactly opposite impact on the AuNP inner filter effect and SERS enhancement. This research provides critical new insights regarding SEAS signal variation and offers a simple methodology for reliable determination of the SERS enhancement factors.

Journal Title

Analytical Chemistry

Volume

84

Issue/Number

20

Publication Date

1-1-2012

Document Type

Article

Language

English

First Page

8437

Last Page

8441

WOS Identifier

WOS:000309805200002

ISSN

0003-2700

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