Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

    Authors

    P. Peng; C. M. Wang; Z. Shi; V. K. Johns; L. Y. Ma; J. Oyer; A. Copik; R. Igarashi;Y. Liao

    Comments

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    Abbreviated Journal Title

    Org. Biomol. Chem.

    Keywords

    CARBON-MONOXIDE RELEASE; HYDROGEN-SULFIDE; COMPLEXES; PRECURSOR; DELIVERY; CORMS; DRUG; MICE; Chemistry, Organic

    Abstract

    Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic alpha-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.

    Journal Title

    Organic & Biomolecular Chemistry

    Volume

    11

    Issue/Number

    39

    Publication Date

    1-1-2013

    Document Type

    Article

    Language

    English

    First Page

    6671

    Last Page

    6674

    WOS Identifier

    WOS:000325119600001

    ISSN

    1477-0520

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