A Series of Fluorene-Based Two-Photon Absorbing Molecules: Synthesis, Linear and Nonlinear Characterization, and Bioimaging
Abbreviated Journal Title
J. Org. Chem.
Keywords
PHOTOPHYSICAL PROPERTIES; OPTICAL-PROPERTIES; FLUORESCENCE; DERIVATIVES; ABSORPTION; DESIGN; MICROFABRICATION; CHROMOPHORES; DYES; Chemistry, Organic
Abstract
The synthesis, structural, and photophysical characterization of a series of new fluorescent donor acceptor and acceptor-acceptor molecules, based on the fluorenyl ring system, with two-photon absorbing properties is described. These new compounds exhibited large Stokes shifts, high fluorescence quantum yields, and significantly, high two-photon absorption cross sections, making them well suited for two-photon fluorescence microscopy imaging. Confocal and two-photon fluorescence microscopy imaging of COS-7 and HCT 116 cells incubated with probe I showed endosomal selectivity, demonstrating the potential of this class of fluorescent probes in multiphoton fluorescence microscopy.
Journal Title
Journal of Organic Chemistry
Volume
75
Issue/Number
12
Publication Date
1-1-2010
Document Type
Article
DOI Link
Language
English
First Page
3975
Last Page
3982
WOS Identifier
ISSN
0022-3263
Recommended Citation
"A Series of Fluorene-Based Two-Photon Absorbing Molecules: Synthesis, Linear and Nonlinear Characterization, and Bioimaging" (2010). Faculty Bibliography 2010s. 6952.
https://stars.library.ucf.edu/facultybib2010/6952
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